Value of albumin dialysis therapy in severe liver insufficiency
نویسندگان
چکیده
منابع مشابه
Teicoplanin pharmacokinetics during albumin dialysis
Teicoplanin (TP) pharmacokinetics was assessed in a critically ill patient during albumin dialysis (AD), which was performed with the molecular adsorbent recirculating system. After a 1200-mg loading dose (24 mg/kg), doses of 1200 and 1000 mg (20 mg/kg) on day 2 and 3, respectively, were administered during two cycles of AD. The mean TP peak and trough concentrations amounted to 99.3 and 21.4 µ...
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OBJECTIVE Acute liver failure (ALF) is haemodynamically characterized by a hyperdynamic circulation. The aims of this study were to investigate the systemic and regional haemodynamics in ALF, to measure changes in nitric oxide metabolites (NOx) and to evaluate whether these haemodynamic disturbances could be attenuated with albumin dialysis. MATERIAL AND METHODS Norwegian Landrace pigs (23-30...
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Dialysis and adsorption processes are commonly implemented in liver support devices for the removal of albumin-bound toxins such as tryptophan. In this work, dialysis and adsorption of tryptophan from albumin-containing solutions were investigated; in particular, the effect of albumin concentration on both processes was analysed. Theoretical models accounting for albumin-tryptophan binding were...
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متن کاملBench-to-bedside review: Current evidence for extracorporeal albumin dialysis systems in liver failure
Acute liver failure (ALF) and acute on chronic liver failure (AoCLF) carry a high mortality. The rationale for extracorporeal systems is to provide an environment facilitating recovery or a window of opportunity for liver transplantation. Recent technologies have used albumin as a scavenging molecule. Two different albumin dialysis systems have been developed using this principle: MARS (Molecul...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2004
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2004.tb00500.x